NVS-PI3-4 bound to the PI3Kg catalytic subunit p110 gamma
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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NVS-PI3-4 bound to the PI3Kg catalytic subunit p110 gamma Descriptor: N~3~-{[5-(4-acetylphenyl)-4-methyl-1,3-thiazol-2-yl]carbamoyl}-N-tert-butyl-beta-alaninamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Authors: Burke, J.E, Rathinaswamy, M.K, Harris, N.J. Deposit date: 2020-08-26 Release date: 2021-03-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Disease related mutations in PI3K gamma disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors. Elife, 10, 2021
创建时间：
2020-08-26
