A crystal structure of EGFR(T790M/V948R) in complex with LN3754
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A crystal structure of EGFR(T790M/V948R) in complex with LN3754 Descriptor: Epidermal growth factor receptor, MAGNESIUM ION, N-(3-{5-[2-(acetylamino)pyridin-4-yl]-2-(methylsulfanyl)-1H-imidazol-4-yl}phenyl)-2-[(1-oxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzamide, ... Authors: Heppner, D.E, Eck, M.J. Deposit date: 2020-03-25 Release date: 2021-03-31 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Design of a "Two-in-One" Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites. J.Med.Chem., 65, 2022
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2020-03-25
