Ten day time course of the effect of influenza A infection on mediastinal lymph node gene expression in mice. Mus musculus

These data were generated as part of a study to model gene regulatory networks influenced by influenza infection. Other tissue compartments included in the study were blood, lung, and spleen. Overall design: RNA was extracted from mediatinal lymph nodes of female mice that did not have any experimental treatment (n = 3, labeled as T-9) or that received intranasal administration of influenza A virus either immediately before (n = 3, T0) or 1 to 10 days before being euthanized for tissue collection (T1 through T10, n =3 per day). Gene expression profiles were determined with comprehensive microarrays (Affymetrix Mouse Gene ST 1.0).