Crystal Structure of 24 bound to the PH domain of Btk

Crystal Structure of 24 bound to the PH domain of Btk Descriptor: (6S)-6-(4-chlorophenyl)-4,5,6,7-tetrahydro-1-benzofuran-3-carboxylic acid, MAGNESIUM ION, Tyrosine-protein kinase BTK, ... Authors: Brear, P, West, R.M, Nicolescu, R.C.B, Blaszczyk, B.K, Anwar, A, Deingruber, T, Sanders, M.G, Perez-Areales, F.J, Stephens, L.R, Hawkins, P.T, Spring, D.R, Hyvonen, M. Deposit date: 2025-06-16 Release date: 2026-05-20 Last modified: 2026-07-29 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Targeting a Pleckstrin Homology Domain with a Lysine-Reactive Covalent Binder. J.Med.Chem., 69, 2026