Results of the comparison of Q0 carrier state for the C4B gene (absolute numbers are in parentheses).

p_contr_trend: p value for trend test of C4B*Q0 frequencies in the three control subgroups (Armitage trend test; secondary endpoint).p_case: p value for the comparison of C4B*Q0 frequencies in the two case subgroups (Fisher's exact test; secondary endpoint).p_trend: p value for trend test of C4B*Q0 frequencies in all five age groups (Armitage trend test; secondary endpoint).p_case_contr: p value for the comparison of C4B*Q0 frequencies between long-lived cases (whole sample) and all younger controls (Fisher's exact test; primary endpoint).n = number; y = years.