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PHF6 regulates stress susceptibility in the pituitary intermediate lobe [CUT&Tag]

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE270455
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We revealed that stress triggers PHF6 to bind to the promoters of various stress-regulated genes in IL-melanotrophic cells and regulate their expression levels. CUT&Tag assays were conducted using a PHF6 antibody on enriched pituitary tissue obtained within 3 hours (8 AM - 11 AM) from 100 control and 100 RS-treated wild-type mice (6-7 weeks old), followed by high-throughput sequencing.
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2025-10-02
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