Crystal structure of a glutaminyl cyclase in complex with NHV-1009
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Crystal structure of a glutaminyl cyclase in complex with NHV-1009 Descriptor: 1-(cyclopentylmethyl)-1-[3-methoxy-4-(2-morpholin-4-ylethoxy)phenyl]-3-[3-(5-methylimidazol-1-yl)propyl]urea, Glutaminyl-peptide cyclotransferase, ZINC ION Authors: Lee, J.W, Song, J.Y, Jang, T.H, Ha, J.H. Deposit date: 2020-07-23 Release date: 2021-12-22 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer's agents by the combination of pharmacophore-based and structure-based design. Eur.J.Med.Chem., 226, 2021
创建时间：
2020-07-23
