Expression data from parental and SLX4IP-depleted D2.OR cells. Expression data from parental and SLX4IP-depleted D2.OR cells

Loss of SLX4IP elicits the metastatic outgrowth of nonmetastatic breast cancer cells by activating Wnt signaling to induce telomere maintenance mechanism switching We sought to assess genome-wide transcriptomic profiles governed by loss of SLX4IP expression in latent D2.OR breast cancer cells Overall design: We propagated parental and SLX4IP-depleted D2.OR cells in 3D-culture for 7 days, at which point total RNA was isolated and subsequently subjected to Affymetrix GeneChip Mouse Gene 2.0 ST Array analysis. Arrays were peformed in triplicate for each cell line.