Big problems from the little brain - novel insights on the Cerebellar Cognitive Affective Syndrome

Datasets of the articles inlcuded in the PhD thesis: Big problems from the little brain - novel insights on the Cerebellar Cognitive Affective Syndrome (CCAS).
Research was carried out in patients with cerebellar disease, focusing on cognitive and affective symptoms.
- Questionnaire study: this dataset contains data gathered via questionnaires, filled in by cerebellar patients and informants. Questions regarding (subjective) cognitive complaints (about executive functioning, attention, and social cognition) and the impact on daily life were asked.
- Cerebellar stroke study: this dataset contains information about a cohort of cerebellar stroke patients (from the ODYSSEY study). Data about the stroke and a large variety of neuropsychological tests is included, to evaluate the prevalence and course of cognitive impairment in this group. Most cognitive data is available for two timepoints: the subacute phase (<9 months after stroke) and chornic phase (>9 months after stroke).
- Meta-analysis: this dataset contains extracted data from 129 studies we used for our meta-anlaysis regarding cognitive performance in patients with cerebellar disorder. Outcomes were neuropsychological test results of patients with primary cerebellar disease, as compared with healthy control data or normative data.
- Validation study: this dataset contains cognitive data of patients with cerebellar disease and healthy control participants. All subjects performed the CCAS scale. All patients also performed a neuropsychological test battery. Validity was evaluated in terms of sensitivity and specificity. Also speech rate was assessed to determine the influence of dysarthria on cognitive outcomes.
- tDCS trial: this dataset contains trial data of an RCT using cerebellar tDCS for CCAS. 35 patients with either a degenerative cerebellar ataxia or cerebellar stroke were included. Cognitive and motor outcomes were gathered before and after the intervention with tDCS, with follow-up moments up to 1 year.