Nickel-Catalyzed Oxidative Coupling Reaction of Phenyl Benzyl Sulfoxides
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https://figshare.com/articles/dataset/Nickel-Catalyzed_Oxidative_Coupling_Reaction_of_Phenyl_Benzyl_Sulfoxides/7068881
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资源简介：
A novel method to produce disulfoxides
diastereoselectively from phenyl benzyl sulfoxides is reported. The
Ni(PnBu3)2Cl2]/NIXANTPHOS catalyst system successfully promotes an oxidative
coupling reaction of aryl benzylic sulfoxides to disulfoxides. An
intermediate aldehyde, produced from the elimination of α-hydroxy
sulfoxides, is proposed to generate the key sulfenate anion, enabling
the formation of the disulfoxide product. A range of disulfoxides
was produced in moderate to high yields (30–83%) and diastereoselectivity
(rac/meso ranging from 3:1 to >20:1).
创建时间：
2018-09-10
