five

EGFR kinase (T790M/L858R) with inhibitor compound 4

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4rj6
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EGFR kinase (T790M/L858R) with inhibitor compound 4 Descriptor: Epidermal growth factor receptor, N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-2-(1H-pyrazol-4-yl)-3H-imidazo[4,5-c]pyridin-6-amine, SULFATE ION Authors: Eigenbrot, C, Yu, C. Deposit date: 2014-10-08 Release date: 2014-11-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Discovery of Selective and Noncovalent Diaminopyrimidine-Based Inhibitors of Epidermal Growth Factor Receptor Containing the T790M Resistance Mutation. J.Med.Chem., 57, 2014
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2014-10-08
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