Table_1_Interactions Between Brain 18F-FDG PET Metabolism and Hemodynamic Parameters at Different Ages of Life: Results From a Prospective Cross-Sectional Study.DOCX

Brain 18F-FDG PET imaging is useful to characterize accelerated brain aging at a pre-symptomatic stage. This study aims to examine the interactions between brain glycolytic metabolism and hemodynamic parameters in different age groups.Methods: A total of 72 patients (from 23 to 88 years of age, 38 women) without any cerebral diseases but with available cardiac, arterial peripheral, and central blood pressure measurements as well as arterial stiffness parameters obtained from brachial pressure and applanation tonometry and a brain 18F-FDG PET scan were prospectively included into this study. Quantitative voxel-to-voxel analyses were carried out to test for negative associations between brain glycolytic metabolism and individual hemodynamic parameters (p-voxel of

脑部18F-FDG正电子发射断层扫描成像技术在无症状期对加速大脑衰老进行表征方面具有重要价值。本研究旨在探讨不同年龄组中脑糖酵解代谢与血流动力学参数之间的相互作用。方法：共纳入72名患者（年龄范围在23至88岁之间，女性38名），这些患者未患有任何脑部疾病，但具有可用的心脏、动脉外周和中枢血压测量值以及通过肱动脉血压和触诊式脉搏描记法获得的动脉硬度参数，并进行了脑部18F-FDG正电子发射断层扫描。对定量体素进行逐体素分析，以检验脑糖酵解代谢与个体血流动力学参数之间的负相关性（p-体素）。