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Reading ADP-ribosylation signalling using chemical biology and interaction proteomics

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NIAID Data Ecosystem2026-03-13 收录
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https://www.omicsdi.org/dataset/pride/PXD024233
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In this project, we describe a global, proteome-wide screening for ADP-ribosylation interactome. Our data reveals novel MAR and PAR readers. We identify both cell type-dependent and independent ADPr interactors. In addition, we quantify apparent binding affinities of large number of ADPr readers. We also identify proteins, whose interaction with ADPr modifications is regulated upon DNA damage induction.
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2021-11-02
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