Gut Microbiome Alterations in Fructose and Food Preservative-Induced Non-Alcoholic Fatty Liver Disease

This study investigates the synergistic effects of fructose and common food preservatives (sodium benzoate, sodium nitrite, and potassium sorbate) on the development of non-alcoholic fatty liver disease (NAFLD) using a human-microbiota-associated mouse model. The project examines changes in the gut microbiome composition through 16S rRNA gene sequencing of fecal samples. The data provide insights into how dietary fructose and food additives impact bacterial communities in the context of NAFLD, revealing significant shifts in microbial diversity and abundance. This dataset contributes to our understanding of the complex interactions between diet, gut microbiota, and liver health, with potential implications for NAFLD prevention and treatment strategies.