Synthesis and in vitro studies for structure-based design of novel chalcones as antitubercular agents targeting InhA - SUPPLEMENTARY FILES FOR TABLES.docx

Table 1. Structure of the prepared chalcones 

Table 2. Synthesis of Chalcone Derivatives

Table 3. Docking Score and Interactions of Designed Chalcone Derivatives

Table 4. Physicochemical Properties of the designed Inhibitors

Table 5. Toxicity Profile of the designed Chalcone Derivatives

Table 6. In-silico Pharmacokinetic Profile of the designed Chalcone Derivatives

Table 7. Bioactivity Score and Medicinal Chemistry of the designed Chalcone Derivatives

Table 8. Antimycobacterial activity of Chalcone Derivatives