Contains 1. significantly differentially expressed genes between samples with high and low gleason grade ("Gleason_high_low"), 2. the pathway overrepresentations for these genes ("MSigDB_Gleason_HL",
Abstract: Epithelial ovarian carcinomas (OC) are particularly deadly due to intratumoral heterogeneity, resistance to standard-of-care therapies, and poor response to alternative treatments such as im
Introduction TP53 mutation carrier (Li-Fraumeni Syndrome, LFS) cohort studies often suffer from lack of extensive pedigree exploration. Methods We performed a nation-wide exploration of TP53 mutation