Project Score dataset release 1

Figshare2022-02-25 更新2026-04-28 收录

CRISPR-Cas9基因编辑

sgRNA效率预测

数据链接：

https://figshare.com/articles/dataset/Project_Score_dataset_release_1/19236978 数据链接链接失效反馈

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资源简介：

Project score dataset (release 1), containing sgRNA-level fold-changes and pre-processed with CRISPRcleanR for the correction of gene-independent response to CRISPR-Cas9 targeting

创建时间：

2022-02-25

Crystal structure of xCas9 P411T

蛋白质晶体结构解析

CRISPR-Cas9基因编辑

Crystal structure of xCas9 P411T Descriptor: CRISPR-associated endonuclease Cas9/Csn1 Authors: Bao, R, Liu, H.Y, Luo, Y.Z, Song, Y.J. Deposit date: 2021-09-29 Release date: 2022-04-06 Last modified: 2

Protein Data Bank Japan2023-11-29 更新50

Decorating chromatin for enhanced genome editing using CRISPR-Cas9

CRISPR-Cas9基因编辑

同源定向修复

To improve the efficiency of homology-directed repair of double-stranded breaks introduced by CRISPR-Cas9, a Cas9-PRDM9 (PR/SET Domain 9) fusion protein was generated and tested in HEK-293T cells. RNA

NIAID Data Ecosystem20

Additional file 7 of A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG

干细胞基因调控

CRISPR-Cas9基因编辑

: Table S4. KEGG pathway enrichment analysis for differentially expressed genes identified using RNA-Seq data obtained from NANOG tdTomato knock-in positive PC-iPS cells vs. WT PC-iPS cells.

NIAID Data Ecosystem10

CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome

朊病毒蛋白

CRISPR-Cas9基因编辑

The molecular function of the cellular prion protein (PrPC) and the mechanism by which it may contribute to neurotoxicity in prion diseases and Alzheimer’s disease (AD) are only partially understood.

NIAID Data Ecosystem20

DataSheet2_Whole genome sequencing of CCR5 CRISPR-Cas9-edited Mauritian cynomolgus macaque blastomeres reveals large-scale deletions and off-target edits.xlsx

CRISPR-Cas9基因编辑

非人灵长类基因组学

Introduction: Genome editing by CRISPR-Cas9 approaches offers promise for introducing or correcting disease-associated mutations for research and clinical applications. Nonhuman primates are physiolog

NIAID Data Ecosystem20

Project Score dataset release 1

资源简介：

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