TOP1

ENCODES a protein that exhibits ATP binding (ortholog); chromatin binding (ortholog); chromatin DNA binding (ortholog); INVOLVED IN animal organ regeneration (ortholog); cellular response to luteinizing hormone stimulus (ortholog); chromatin remodeling (ortholog); PARTICIPATES IN irinotecan pharmacodynamics pathway; irinotecan pharmacokinetics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); disease of cellular proliferation (ortholog); Disease Progression (ortholog); FOUND IN cytoplasm (ortholog); dense fibrillar component (ortholog); fibrillar center (ortholog)

编码一种具有ATP结合（同源）特性的蛋白质；染色质结合（同源）；染色质DNA结合（同源）；参与动物器官再生（同源）；对促黄体生成素刺激的细胞反应（同源）；染色质重塑（同源）；参与伊立替康药代动力学通路；伊立替康药效学通路；与自闭症谱系障碍（同源）相关；细胞增殖疾病（同源）；疾病进展（同源）；存在于细胞质（同源）；致密纤维成分（同源）；纤维中心（同源）