Correlation between liver metastasis and SPP1 or LEF1 overexpressiona.

aAs a predictor for liver metastasis, the sensitivity, specificity, positive predictive value, and negative predictive value for overexpression of SPP1 in the primary colon cancer tissue were 26.7%, 83.6%, 70.6%, and 70.6%, respectively. In contrast, the sensitivity, specificity, positive predictive value, and negative predictive value for overexpression of LEF1 are 28.1%, 86.3%, 61.5%, and 60.6%, respectively. Despite that the sensitivity and specificity were higher in LEF1, both showed modest performance.