Expression data from whole blood sample of eight kinds of TCM syndromes of rheumatoid arthritis patients.

To explore the biological connotation of eight syndromes of Rheumatoid Arthritis (RA) from the syndrome-symptom association network, and the relationship between the clinical characteristics of various syndromes and their key network target genes and pathways, which may offer clinicians auxiliary tools for diagnosis and treatment of RA patients with various traditional Chinese medicine (TCM) syndromes and promoting the developments of TCM Syndrome Theory. We used microarrays to detail the biological connotation of five syndromes (D-H, N) of Rheumatoid Arthritis (RA) and identified distinct classes of up-regulated and down-regulated genes during this process. Three to four RA patients cases per syndrome group respectively with Damp Heat Obstruction Syndrome (A), Phlegm Stasis Obstruction Syndrome (B), Qi-Yin Deficiency Syndrome (C), Blood Stasis Syndrome (D), Qi-Blood Deficiency Syndrome (E), Liver and Kidney Deficiency Syndrome (F), Wind-dampness Obstruction Syndrome (G) and Cold-dampness obstruction syndrome (H) were collected as RA group, and seven healthy people were collected as normal control group (N).