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Wnt-Activating Human Skin Organoid Model of Atopic Dermatitis Induced by Staphylococcus aureus and Its Protective Effects by Cutibacterium acnes

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP394142
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We investigated transcriptional changes associated with S. aureus infection by performing RNA sequencing. the goal of this transcriptome analysis was to confirm ALI-skin organoids can capture the host cellular responses against bacterial infection including bacterial recognition and inflammatory signaling. Overall design: The total RNA was extracted from three biological replicates of ALI-skin organoids after treatment with S. aureus (106 CFU) for 18 hrs
创建时间:
2023-03-01
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