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Crystal structure of PDE4D catalytic domain in complex with compound 36

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Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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Crystal structure of PDE4D catalytic domain in complex with compound 36 Descriptor: (1S)-1-[(7-chloranyl-1H-indol-3-yl)methyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carbaldehyde, 1,2-ETHANEDIOL, MAGNESIUM ION, ... Authors: Zhang, X.L, Xu, Y.C. Deposit date: 2020-06-12 Release date: 2021-06-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment. Eur.J.Med.Chem., 211, 2021
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2020-06-12
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