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Role of Stat3 in Fcgr2b mediated HPCs differentiation from tumor-bearing mice

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP299417
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Fcgr2b deficient mice showed a decreased number of MDSCs infiltration in tumor microenvironment. To determine the role of Fcgr2b involving in HPCs differentiation. Total RNA was isolated from sorted BM HPCs from MC38 tumor-bearing WT or KO mice. Fcgr2b promoted the generation of MDSCs from HPCs through activation Stat3 signling.
创建时间:
2021-03-04
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