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Selective N‑Formylation of Amines with H2 and CO2 Catalyzed by Cobalt Pincer Complexes

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Figshare2017-03-08 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Selective_i_N_i_Formylation_of_Amines_with_H_sub_2_sub_and_CO_sub_2_sub_Catalyzed_by_Cobalt_Pincer_Complexes/4733248
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N-formylation of amines utilizing CO2 in the presence of reducing agents constitute an important methodology in organic synthesis. Presented herein is a selective N-formylation of amines with CO2 and H2 catalyzed by complexes of Earth-abundant cobalt. A wide range of amines were converted to their corresponding formamides under CO2 and H2 pressure, catalyzed by Co-PNP pincer complex, generating water as the sole byproduct.
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2017-03-08
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