Direct evidence that naturally occurring mutations within hepatitis B core epitope alter CD4+ T-cell reactivity.
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This peptide is an analog of the naturally occurring HBV core 50-69 epitope, with randomly introduced mutations at positions 11 (L to V) and 20 (A to G). This peptide is an analog of the naturally occurring HBV core 50-69 epitope, with randomly introduced mutations at positions 11 (L to V) and 20 (A to G). It elicited T-cell proliferative responses in three patients with chronic hepatitis B.
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IEDB创建时间：
2004-01-01
