Identification of Lead Drug Candidates for COVID-19 based on Drug Screening Using Human Pluripotent Stem Cell-Derived Cells/Organoids

Name: Identification of Lead Drug Candidates for COVID-19 based on Drug Screening Using Human Pluripotent Stem Cell-Derived Cells/Organoids
Creator: Weill Cornell Medicine
Published: 2022-02-20T00:00:00+08:00

干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录

病毒感染

器官模型

数据链接：

http://data.iscr.ac.cn/Article?id=d1ce0e3882d7bccf94dc71bf0034a8be 数据链接链接失效反馈

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资源简介：

We systematically probed which cell types are permissive to SARS-CoV-2 infection. Transcriptomic analysis following SARS-CoV-2 infection of hPSC-derived pancreatic and lung organoids revealed upregulation of chemokines but not type I/III interferon signaling, similar to what was seen in primary human COVID-19 pulmonary infection.

提供机构：

Weill Cornell Medicine

创建时间：

2022-02-20