Evolutionary transcriptomics of Eutherian gene expression gains and the origins of decidualization [Set 1]

We used human endometrial stromal fibroblast cell line to perform an siRNA knockdown coupled with RNA-seq screen of a series of transcription factors that gained expression in the endometrial tissue of Eutherian mammals. Overall design: mRNA-Seq in ESF cells treatd with negative control siRNAs or siRNA targeting a series of human transcription factors