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Transcriptomic effects of SET7 repression in human breast cancer cells

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE163017
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SET7 is a histone methyltransferase suggested to influence gene expression by modifying local chromatin at H3K4me1. RNA-sequencing experiment aimed at identifying the genes regulated by SET7 in MDA-MB-231 cells after SET7 repression. Then comparing the results with those obtained from RNA-seq data after ERRα inactivation (GSE49110) allowed to identify genes regulated by ERRα and SET7. MDA-MB231 cells were inactivated for SET7 using two different siRNAs. One control siRNA was used for comparison. In each condition, triplicate samples were analyzed.
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2021-06-11
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