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Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator

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Protein Data Bank Japan2024-11-27 更新2026-03-21 收录
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https://pdbj.org/mine/summary/3o6i
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Ligand-binding domain of GluA2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator Descriptor: 2-[({3-tert-butyl-4-[(methylamino)methyl]-1H-pyrazol-1-yl}acetyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, GLUTAMIC ACID, Glutamate receptor 2, ... Authors: Maclean, J.K.F, Campbell, R.A, Cumming, I.A, Gillen, K.J, Gillespie, J, Jamieson, C, Kazemier, B, Kiczun, M, Lamont, Y, Lyons, A.J, Martin, F, Moir, E.M, Morrow, J.A, Pantling, J, Rankovic, Z, Smith, L. Deposit date: 2010-07-29 Release date: 2010-09-15 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A novel series of positive modulators of the AMPA receptor: structure-based lead optimization. Bioorg.Med.Chem.Lett., 20, 2010
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2010-07-29
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