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Inhibitory NK receptor expression associates with altered antimalarial function of gd T cells

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DataCite Commons2026-01-23 更新2026-05-03 收录
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https://www.immport.org/shared/study/SDY3207
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The goal of the study was to characterize inhibitory NK receptor (NKR) expression and function on gamma delta T cells from children with different malaria exposure histories. Using spectral flow cytometry to immunoprofile peripheral blood samples, we identified divergent NKR expression on major gamma delta T cell subsets. Further, we observed altered functional responses to TCR- and FcR-mediated stimulation among NKR-expressing Vg9Vd2 T cells, pointing to a role in modulating their response to malaria.
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ImmPort
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2026-01-23
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