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Expression of DNA replication proteins in control and hypertrophied hearts.

NIAID Data Ecosystem2026-03-07 收录

数据链接：

https://figshare.com/articles/dataset/_Expression_of_DNA_replication_proteins_in_control_and_hypertrophied_hearts_/295277 数据链接链接失效反馈

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资源简介：

All values are mean ±SD; ns-non-significant; *P<0.05 vs control.

应用场景：

创建时间：

2012-06-14

发育表观遗传学

心肌肥厚分子机制

Methylation at 5-cytosine (5-mC) is a fundamental epigenetic DNA modification associated recently with cardiac disease. In contrast, the role of 5-hydroxymethylcytosine (5-hmC) – 5-mC’s oxidation prod

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Structural basis of focal adhesion targeting domain-mediated signaling in cardiac hypertrophy

心肌肥厚分子机制

构象动力学

The focal adhesion targeting (FAT) domain of focal adhesion kinase (FAK) exists in monomeric closed (c) or arm exchanged (ae) dimeric state. FAT interaction with Grb2 necessitates an intermediate open

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Syndecan-4 Is Essential for Development of Concentric Myocardial Hypertrophy via Stretch-Induced Activation of the Calcineurin-NFAT Pathway

心肌肥厚分子机制

NFAT转录因子

Sustained pressure overload leads to compensatory myocardial hypertrophy and subsequent heart failure, a leading cause of morbidity and mortality. Further unraveling of the cellular processes involved

Figshare2016-01-18 更新20

GO:0010611 (regulation of cardiac muscle hypertrophy)

心肌肥厚分子机制

基因调控网络

This network was assembled automatically by INDRA (http://indra.bio) by processing all available biomedical literature with multiple machine reading systems, and integrating curated pathway databases.

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TICRR and MTBP are cell cycle regulated

细胞周期调控

DNA复制蛋白表达

To determine how levels of DNA replication proteins change during the cell cycle.

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