Plcg2

ENCODES a protein that exhibits phosphatidylinositol phospholipase C activity; phosphorylation-dependent protein binding (ortholog); phosphotyrosine residue binding (ortholog); INVOLVED IN intracellular signal transduction; positive regulation of cell cycle G1/S phase transition; positive regulation of cytosolic calcium ion concentration; PARTICIPATES IN erythropoietin signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; B cell receptor signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); autoinflammation, antibody deficiency, and immune dysregulation syndrome (ortholog); B-Cell Chronic Lymphocytic Leukemia (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); intracellular vesicle (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide

编码一种表现出磷脂酰肌醇磷脂酶C活性的蛋白质；磷酸化依赖性蛋白结合（同源）；磷酸酪氨酸残基结合（同源）；参与细胞内信号转导；正调控细胞周期G1/S期转换；正调控细胞质钙离子浓度；参与促红细胞生成素信号通路；磷脂酰肌醇3激酶I类信号通路；B细胞受体信号通路；与阿尔茨海默病（同源）相关；自身炎症、抗体缺乏和免疫失调综合征（同源）；与B细胞慢性淋巴细胞白血病（同源）相关；存在于细胞质（同源）、细胞溶质（同源）和细胞内囊泡（同源）；与2,3,7,8-四氯二苯并二恶英、6-丙基-2-硫尿嘧啶和乙酰胺相互作用。