Pulmonary mRNA levels of pattern-recognition receptors.
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https://figshare.com/articles/dataset/_Pulmonary_mRNA_levels_of_pattern_recognition_receptors_/203635
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Animals were pre-treated with uricase (0.2 mg/kg), allopurinol (25 mg/kg), or vehicle (10% dimethylsulfoxide) and were mechanically ventilated for 5 hours (MV), non-ventilated vehicle pre-treated mice served as controls (C). Gene expression levels of Toll-like receptor (TLR) 2, TLR4, and, NLRP3 were measured in lung tissue homogenates and normalized to the house-keeping gene hypoxanthine-guaninephosphoribosyl transferase (HPRT). Data represent mean ± SEM of n = 4 non-ventilated mice and n = 8−9 ventilated mice/group.
**p<0.01 versus non-ventilated controls.
创建时间:
2012-11-30



