Transcription profile of WT and LKB1 (encoded by the gene Stk11)-deficient Treg cells. Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA324713
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资源简介：
LKB1 deficiency in Treg cells impairs their survival, metabolism and suppressive function. To exclude the impact of excessive inflammation on LKB1-deficient Treg cells, we generated mixed bone marrow (BM) chimeras using Foxp3-Cre WT and Foxp3-Cre Stk11 fl/fl BM cells, together with CD45.1+ BM cells. We used microarray to compare the global transcription profile of dornor-derived LKB1-deficient Tregs with WT counterparts. Overall design: In total 10 samples; 5 sampels WT Treg cells and 5 samples of LKB1-deficient Treg cells
创建时间：
2016-06-07
