Metastatic brain tumor

Interaction between microRNAs (miRNAs) and abnormal methylation to control metastasis. Tumor growth and metastasis formation through down regulation of their oncogenic targets such as MYC, E2F3 and cyclin-dependent kinase(CDK6). Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP2249 CPTAC Assay Portal]miRNA（微小RNA）与异常甲基化的相互作用及其在控制转移中的作用。通过下调其致癌靶标，如MYC、E2F3和细胞周期依赖性激酶（CDK6），肿瘤的生长和转移形成。该通路上的蛋白质具有通过CPTAC检测门户（[https://assays.cancer.gov/available_assays?wp_id=WP2249 CPTAC检测门户]）可用的靶向检测。