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Functional maturation of rat beta cells
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创建时间：
2016-07-27
相关数据集
Islet-specific microRNA changes driven by nutrient shift trigger postnatal beta-cell maturation - dispersed islet cell mRNAs after miR-17-5p transfection. Rattus norvegicus
We found that in rodents, postnatal beta-cell maturation is associated with changes in the expression of several islet microRNAs and discovered that these modifications are driven by changes in the nu
NIAID Data Ecosystem80
High-throughput single cell transcriptome analysis and CRISPR screen identify key β cell-specific disease genes. High-throughput single cell transcriptome analysis and CRISPR screen identify key β cell-specific disease genes
Pancreatic endocrine cells orchestrate the precise control of blood glucose levels, but the contribution of each cell type to diabetes or obesity remains elusive. Here we used a massively parallel sin
NIAID Data Ecosystem50
Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories toward type 2 diabetes. Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories toward type 2 diabetes
To gain insight into the history of islet cell deterioration along the progression from normal glycemic regulation to T2D, we collected surgical pancreatic tissue samples from 133 metabolically phenot
NIAID Data Ecosystem40
RNA-seq to compare wild type, db/+ and db/db islets
Purpose: RNA seq analysis were to compare and contrast the gene expression profile involved in the dedifferentiation of db/db islets in type 2 diabetes Methods: Islets of wild type, db/+ and db/db wer
Alliance of Genome Resources60
Supplementary Material for: The Placental Secretome: Identifying Potential Cross-Talk Between Placenta and Islet β-Cells
Background/Aims: Insulin-secreting islet β-cells adapt to the insulin resistance associated with pregnancy by increasing functional β-cell mass, but the placental signals involved in thi
DataCite Commons2025-05-01 更新50
