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Crystal structure of cMET kinase domain bound by compound 9Y

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Protein Data Bank Japan2023-11-29 更新2026-03-28 收录
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资源简介:
Crystal structure of cMET kinase domain bound by compound 9Y Descriptor: Hepatocyte growth factor receptor, ~{N}-methyl-4-[1-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-oxidanylidene-pyridazin-3-yl]-2-(trifluoromethyl)benzamide Authors: Qu, L.Z, Chen, Y.H. Deposit date: 2022-06-16 Release date: 2022-11-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.26 Å) Cite: Discovery of D6808, a Highly Selective and Potent Macrocyclic c-Met Inhibitor for Gastric Cancer Harboring MET Gene Alteration Treatment. J.Med.Chem., 65, 2022
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2022-06-16
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