Accuracy in change point detection.

a A change point found by CREST at single base pair resolution is considered as detected by another method if there exist two neighboring segments produced by the method such that the change point falls in the gap between the two segments (i.e., between the right boundary of the 5’ segment and the left boundary of the 3’ segment). Display is the percentage of CREST change points detected by the method under consideration.
b The median of per-sample segment number across the samples with CREST-identified change points. Median absolute deviation (MAD) is included in the parentheses.
c The median half size of the gap (measured in kilo base pair, kb) between the segment boundaries harboring a CREST change point. Median absolute deviation (MAD) is included in the parentheses.
d Locus density is defined as the number of loci distributed per million base pair (Mb) on average.
e Since both CNAnorm and Control-FREEC were applied at the resolution of 1kb window, the half size of the gap harboring a CREST change point is exactly 0.5kb.
Accuracy in change point detection.