Summary of the EAE disease coursea.

aGraded disease score as described in Materials and Methods.bRepresents the percentage of mice that developed a clinical score of at least one.cRepresents the percentage of mice that died or were sacrificed for humane purposes.dThe cumulative disease score was calculated by adding the disease score from the day of onset to day 30. The values shown are the mean±SE of all the mice with disease in each group.eNo Tx = No Treatment.fMino = Minocycline.gLipo = Empty PEG-liposomes.hMino = Minocycline.iMino-Lipo = PEG minocycline-liposomes.