Missense mutations identified in patients manifesting with non-classic StAR deficiency.

*Mutation on partner allele is given in brackets (p.).**Loss of function mutation manifesting clinically at birth with signs of classic StAR deficiency. Data given for comparison.***In vitro activity (% of WT) is assessed by pregnenolone production (immunoassay) in COS cells transfected with expression vectors for wild-type or mutant StAR and F2 (the fusion protein P450 side-chain cleavage/adrenodoxin/adrenodoxin reductase). Note that data derive from different laboratories employing similar assay systems.