Structure of BACE1 complex with 2-thiophenyl HEA-type inhibitor

NIAID Data Ecosystem2026-05-02 收录

药物靶点结构解析

阿尔茨海默病药物设计

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资源简介：

Structure of BACE1 complex with 2-thiophenyl HEA-type inhibitor

创建时间：

2024-11-20

Crystal Structure of BACE with Compound 12a

阿尔茨海默病药物设计

BACE-1抑制剂结构生物学

Crystal Structure of BACE with Compound 12a Descriptor: (5R,7S)-1-(3-fluorophenyl)-3,7-dimethyl-8-[3-(propan-2-yloxy)benzyl]-2-thia-1,3,8-triazaspiro[4.5]decane 2,2-dioxide, 1,2-ETHANEDIOL, Beta-secre

Protein Data Bank Japan2024-11-06 更新60

Human Thrombin In Complex With MI330

凝血酶-抑制剂复合物结构

药物靶点结构解析

Human Thrombin In Complex With MI330 Descriptor: (2S)-N-[[2-(aminomethyl)-5-chloranyl-phenyl]methyl]-1-[(2S)-2-[(3-chloranyl-4-methoxy-phenyl)sulfonylamino]-4-[(4-cyanophenyl)methylamino]-4-oxidanylid

Protein Data Bank Japan2024-10-30 更新40

Solid-State NMR, Crystallographic, and Computational Investigation of Bisphosphonates and Farnesyl Diphosphate Synthase−Bisphosphonate Complexes

药物靶点结构解析

药物设计

Bisphosphonates are a class of molecules in widespread use in treating bone resorption diseases and are also of interest as immunomodulators and anti-infectives. They function by inhibiting the enzyme

NIAID Data Ecosystem20

THROMBIN COMPLEXED WITH HIRUGEN AND A BETA-STRAND MIMETIC INHIBITOR

凝血酶抑制剂复合物结构

药物靶点结构解析

THROMBIN COMPLEXED WITH HIRUGEN AND A BETA-STRAND MIMETIC INHIBITOR

NIAID Data Ecosystem40

T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-722

药物靶点结构解析

抗寄生虫药物设计

T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-722

NIAID Data Ecosystem30