Impact of ADRs due to directly observed treatment strategy therapy on smear results at the end of intensive phase and anti-TB treatment outcomes.

ADRs, adverse drug reactions; TB, tuberculosis; OR, odds ratio; CI, confidence internal; AR%, attributable risk proportion; PAR%, population attributable risk proportion.& A total of 518 patients developed ADRs within the intensive phase. For the data of 51 patients missed, 4253 patients’ data were analyzed.$A total of 649 patients developed ADRs at the end of anti-TB treatment. For the data of 16 patients missing, 4288 patients’ data was analyzed. Successful outcomes defined as the completion of treatment and patients being cured. Unsuccessful outcomes defined as treatment failure, default and death because of ADRs due to DOTS therapy.*Age, gender, TB treatment history and disease history were adjusted using logistic regression analysis.§Age, gender, TB treatment history and HBsAg status were adjusted using logistic regression analysis.#AR% and PAR% were calculated based on adjusted OR, respectively.