Crystal structure of the catalytic domain of Human MMP12 in complex with a carboxylate inhibitor related to RXP470
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Crystal structure of the catalytic domain of Human MMP12 in complex with a carboxylate inhibitor related to RXP470 Descriptor: (R)-4-(((S)-1-(((S)-1-amino-4-carboxy-1-oxobutan-2-yl)amino)-4-carboxy-1-oxobutan-2-yl)amino)-3-((3-(3'-chloro-[1,1'-biphenyl]-4-yl)isoxazol-5-yl)methyl)-4-oxobutanoate, CALCIUM ION, Macrophage metalloelastase, ... Authors: Rouanet-Mehouas, C, Devel, L, Dive, V, Stura, E.A. Deposit date: 2015-07-28 Release date: 2016-08-10 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Zinc-Metalloproteinase Inhibitors: Evaluation of the Complex Role Played by the Zinc-Binding Group on Potency and Selectivity. J. Med. Chem., 60, 2017
创建时间：
2015-07-28
