five

Structure of AMPK in complex with Cl-A769662 activator and STAUROSPORINE inhibitor

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Protein Data Bank Japan2024-11-27 更新2026-03-21 收录
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Structure of AMPK in complex with Cl-A769662 activator and STAUROSPORINE inhibitor Descriptor: 2-chloro-4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, ... Authors: Calabrese, M.F, Kurumbail, R.G. Deposit date: 2014-05-21 Release date: 2014-08-06 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (3.34 Å) Cite: Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms. Structure, 22, 2014
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2014-05-21
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