Correlation between killing rate constants and properties of simulated CTL.

Spearman's rank correlation coefficient for the estimated killing parameter or and against the CTL hunting velocity , the average CTL velocity and the killing duration , respectively. The estimation was either based on the assumption that targets cells bound in conjugates are counted in the FACS analysis (a) or that they have been killed and therefore not counted (b). Estimates were obtained by using either Eq. (8) (original) or Eq. (9) (revised). For each situation, 1000 data pairs are correlated. ( for all coefficients).