Physiologic data in 14-day -old rats exposed to 1.7% isoflurane or 2.4% sevoflurane by either spontaneous breathing or mechanical ventilation at the end of each hour during 4-hour anesthesia.

Data presented as mean±standard deviation.
IS = Isoflurane spontaneously breathing group; SS = Sevoflurane spontaneously breathing group;
IM = Isoflurane mechanically ventilated group; SM = Sevoflurane mechanically ventilated group.
pH, PaCO2, PO2 and Glu: *P<0.05, **P<0.01, compared with controls.
MAP: *P<0.05, **P<0.01, IS compared with IM, SS compared with SM.