Gene pathways identified by Kyoto Encyclopedia of Genes and Genomes (KEGG) database to be up and downregulated in the DMPA group as compared to controls.
Compared with WT mice, 315 genes were found to be up-regulated in PGC-1α Tg mice by microarray and classified into KEGG pathway analysis as described in Methods.
Total: total number of patients with or without ADRs. Events: number of patients with one or more mutant TPMT alleles (TPMT*3A, TPMT*3B and TPMT*3C) within the ADRs or no ADRs group.
Started in 2007, the Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-ethnicity (SAPPHIRE) is one of the largest asthma cohort studies in the United States. Its overarching goal is