five

ERK5 in complex with a pyrrole inhibitor

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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ERK5 in complex with a pyrrole inhibitor Descriptor: 4-(2-bromanyl-6-fluoranyl-phenyl)carbonyl-~{N}-pyridin-3-yl-1~{H}-pyrrole-2-carboxamide, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 7 Authors: Tucker, J.A, Heptinstall, A, Myers, S. Deposit date: 2017-06-08 Release date: 2018-06-20 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38 alpha and BRD4. Eur.J.Med.Chem., 178, 2019
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2017-06-08
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