Crystal structure of cMET kinase domain bound by D6808
收藏Protein Data Bank Japan2023-11-29 更新2026-04-19 收录
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Crystal structure of cMET kinase domain bound by D6808 Descriptor: (1^4Z,5^2E)-6^3-(trifluoromethyl)-5^1,5^6-dihydro-1^1H-8-aza-2(3,6)-quinolina-5(1,3)-pyridazina-1(4,1)-pyrazola-6(1,4)-benzenacyclododecaphane-5^6,7-dione, Hepatocyte growth factor receptor Authors: Chen, Y.H, Qu, L.Z. Deposit date: 2022-09-15 Release date: 2022-11-23 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Discovery of D6808, a Highly Selective and Potent Macrocyclic c-Met Inhibitor for Gastric Cancer Harboring MET Gene Alteration Treatment. J.Med.Chem., 65, 2022
创建时间：
2022-09-15
