Interaction Network for Acute Myeloid Leukemia (AML) using The Cancer Genome Atlas (TCGA) database

RNA-seq data was downloaded from the TCGA website (Nov 14, 2013) and includes 128 DESEq normalized samples. The data was derived from primary samples of sorted whole blood obtained from AML patients. 100 bootstraps of ARACNe were run using adaptive partitioning, p-value cut off of 1e-8, and full DPI. The regulator list that was used includes all the genes with GO annotation of transcriptional regulation or DNA binding (Shimoni, Yishai; Alvarez, Mariano (2013): TF list. figshare.<br>http://dx.doi.org/10.6084/m9.figshare.871524)